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Product Sizes
10 mg
£151.00
SIH-539-10MG
50 mg
£448.00
SIH-539-50MG
About this Product
SKU:
SIH-539
Additional Names:
Iniparib, 4-Iodo-3-nitrobenzamide, BSI-201, 4-iodo-3-nitro-benzamide, Iniparib (BSI-201)
CAS Number:
160003-66-7
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
BSI 201 is a small molecule inhibitor of poly(ADP-ribose) polymerase 1 (PARP1), an enzyme involved in DNA repair and cellular stress responses. While widely studied in oncology for its ability to induce synthetic lethality in tumor cells with DNA repair deficiencies, PARP1 inhibition is also relevant to neurodegenerative disease research. Excessive PARP1 activation has been linked to neuronal death in conditions such as stroke, Parkinson's disease, and Alzheimer's disease. By modulating DNA repair and inflammatory pathways, BSI 201 may help mitigate neuronal damage and promote neuroprotection. Its dual relevance to cancer and neuroscience underscores its value in translational research.
Molecular Weight:
292
Purity:
>98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors