Leptomycin B
Product Sizes
200 ug
£159.00
SIH-534-200UG
1 mg
£429.00
SIH-534-1MG
About this Product
- SKU:
- SIH-534
- Additional Names:
- Elactocin, LMB, Mantuamycin, NSC 364372
- CAS Number:
- 87081-35-4
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Leptomycin B is a potent inhibitor of nuclear export proteins, specifically targeting CRM1/exportin 1. By blocking the nuclear export of tumor suppressors and regulatory proteins, it has been studied extensively in cancer research. In neuroscience, its ability to modulate nuclear-cytoplasmic transport has implications for neurodegenerative diseases where protein mislocalization contributes to pathology. Leptomycin B serves as a valuable tool in understanding nucleocytoplasmic dynamics in neuronal cells.
- Molecular Weight:
- 540.7
- Purity:
- >99%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/leptomycin-b-sih-534/
