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Product Sizes
5 mg
£216.00
SIH-511-5MG
25 mg
£687.00
SIH-511-25MG
About this Product
SKU:
SIH-511
Additional Names:
SB 431542, 4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamide hydrate, 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide hydrate, 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]-benzamide hydrate
CAS Number:
301836-41-9
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
SB431542 is a selective inhibitor of the TGF-B Beta type I receptor ALK5, as well as ALK4 and ALK7. TGF-B Beta signaling plays a complex role in neuroinflammation, neurogenesis, and synaptic plasticity. In neurodegenerative disease models, SB431542 has been used to modulate glial activation and to investigate the role of TGF-B Beta in neuronal survival and repair. Its application in stem cell research also supports its relevance in regenerative neuroscience.
Molecular Weight:
384.4
Purity:
≥98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors