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Product Sizes
5 mg
£185.00
SIH-510-5MG
25 mg
£521.00
SIH-510-25MG
About this Product
SKU:
SIH-510
Additional Names:
SB 216763, 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
CAS Number:
280744-09-4
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
SB216763 is a potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3), targeting both GSK-3A Alpha and GSK-3B Beta. GSK-3B Beta is a critical enzyme in tau phosphorylation and amyloid precursor protein processing, making SB216763 highly relevant in Alzheimer's disease research. Inhibition of GSK-3 has been shown to promote neurogenesis, enhance synaptic plasticity, and reduce neuroinflammation. SB216763 is widely used in neuroscience to study mechanisms of neurodegeneration and to explore therapeutic strategies for cognitive disorders.
Molecular Weight:
371.2
Purity:
≥98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors