PMA
Product Sizes
1 mg
£132.00
SIH-508-1MG
5 mg
£296.00
SIH-508-5MG
About this Product
- SKU:
- SIH-508
- Additional Names:
- Phorbol 12-myristate 13-acetate
- CAS Number:
- 16561-29-8
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- PMA is a potent phorbol ester widely used as a reversible activator of protein kinase C (PKC). In neuroscience, PMA serves as a critical tool for studying synaptic plasticity, signal transduction, and neuroinflammation. By mimicking diacylglycerol, PMA activates PKC isoforms, influencing neuronal gene expression, neurotransmitter release, and long-term potentiation. Its ability to modulate neuroinflammatory pathways and glial activation makes it relevant in models of neurodegenerative diseases such as Alzheimer's and Parkinson's. PMA is also used to investigate tumor-promoting mechanisms in neural tissues, offering insights into brain cancer biology.
- Molecular Weight:
- 616.8
- Purity:
- ≥99%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/activator/pma-sih-508/
