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Product Sizes
5 mg
£165.00
SIH-504-5MG
25 mg
£448.00
SIH-504-25MG
About this Product
SKU:
SIH-504
Additional Names:
LY 364947, HTS 466284, ALK5 Inhibitor I, 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline, HTS 466284, Transforming Growth Factor-B Beta Type I Receptor Kinase Inhibitor
CAS Number:
396129-53-6
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
LY364947 is a potent and selective inhibitor of TGF-B Beta type I receptor kinase, blocking downstream SMAD signaling. TGF-B Beta signaling is involved in neuroinflammation, synaptic plasticity, and glial activation-processes central to neurodegenerative disease progression. LY364947 has been used to investigate the role of TGF-B Beta in central nervous system disorders, offering insights into therapeutic strategies targeting neuroinflammatory pathways.
Molecular Weight:
272.3
Purity:
≥98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors