Picropodophyllotoxin
Product Sizes
5 mg
£206.00
SIH-467-5MG
25 mg
£646.00
SIH-467-25MG
About this Product
- SKU:
- SIH-467
- Additional Names:
- Picropodophyllin, NSC 36407, PPP, (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
- CAS Number:
- 477-47-4
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Picropodophyllotoxin is an inhibitor of the insulin-like growth factor 1 receptor (IGF1R), blocking its autophosphorylation and downstream signaling. In neuroscience, IGF1R signaling is associated with neuronal growth, survival, and metabolism. Picropodophyllotoxin is used to explore the role of IGF1R in neurodegenerative diseases, particularly in relation to cell cycle regulation, apoptosis, and synaptic maintenance. Its ability to modulate pAKT and pERK1/2 pathways makes it a useful compound for studying neuroprotective and neurotoxic mechanisms in the brain.
- Molecular Weight:
- 414.4
- Purity:
- ≥96%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/picropodophyllotoxin-sih-467/
