PD98059
Product Sizes
5 mg
£165.00
SIH-466-5MG
25 mg
£488.00
SIH-466-25MG
About this Product
- SKU:
- SIH-466
- Additional Names:
- 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one, PD98059
- CAS Number:
- 167869-21-8
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- PD98059 is a potent, selective, and reversible inhibitor of MEK1, a kinase upstream of ERK in the MAPK signaling cascade. It binds to the inactive form of MEK1, preventing its activation and subsequent phosphorylation of ERK. In neurodegenerative disease research, PD98059 is used to study the role of MAPK/ERK signaling in neuronal survival, synaptic plasticity, and memory. It is also employed to investigate the impact of ERK inhibition on neuroinflammation and oxidative stress, making it a valuable tool in models of Alzheimer's and Parkinson's disease.
- Molecular Weight:
- 267.3
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/pd98059-sih-466/
