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Product Sizes
5 mg
£138.00
SIH-465-5MG
25 mg
£356.00
SIH-465-25MG
About this Product
SKU:
SIH-465
Additional Names:
4- [2, 3- dihydro- 3- methyl- 2- oxo- 8- (3- quinolinyl)- 1H- imidazo[4, 5- c]quinolin- 1- yl]- A Alpha, A Alpha- dimethyl- benzeneacetonitrile
CAS Number:
915019-65-7
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
NVPBEZ235 is a dual inhibitor of PI3K and mTOR, with additional activity against ATR. This compound is widely used in neuroscience to investigate the PI3K/Akt/mTOR signaling pathway, which regulates neuronal survival, metabolism, and autophagy. Dysregulation of this pathway is implicated in neurodegenerative diseases, including Alzheimer's and Parkinson's. NVPBEZ235 is employed to study the effects of pathway inhibition on protein aggregation, synaptic function, and neuroinflammation, offering insights into potential therapeutic strategies targeting cellular stress responses in the brain.
Molecular Weight:
469.5
Purity:
≥97%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors