K252A
Product Sizes
100 ug
£136.00
SIH-455-100UG
1 mg
£334.00
SIH-455-1MG
About this Product
- SKU:
- SIH-455
- Additional Names:
- (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
- CAS Number:
- 99533-80-9
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- K252A is a broad-spectrum protein kinase inhibitor that targets a wide range of kinases, including PKA, PKC, PKG, CaM kinase II, myosin light chain kinase (mlCK), and receptor tyrosine kinases. In neuroscience, K252A is widely used to study neurotrophic signaling, particularly through its inhibition of TrkA, the receptor for nerve growth factor (NGF). It is employed in models of neuronal differentiation, survival, and synaptic plasticity. K252A is also used to investigate the role of kinase signaling in neurodegenerative processes and to explore therapeutic strategies targeting kinase dysregulation in the brain.
- Molecular Weight:
- 467.5
- Purity:
- ≥98%
- Shipping Conditions:
- Ambient
- Source:
- Nonomuraea longicatena
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/k252a-sih-455/
