JX 401
Product Sizes
10 mg
£256.00
SIH-454-10MG
50 mg
£819.00
SIH-454-50MG
About this Product
- SKU:
- SIH-454
- Additional Names:
- 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
- CAS Number:
- 349087-34-9
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- JX 401 is a potent and reversible inhibitor of p38A Alpha mitogen-activated protein kinase (MAPK), a key regulator of inflammatory responses and cellular stress signaling. In neurodegenerative disease research, p38A Alpha MAPK is implicated in microglial activation, cytokine production, and neuronal apoptosis. JX 401 is used to investigate the role of p38A Alpha in neuroinflammation and neurotoxicity, particularly in models of Alzheimer's disease, Parkinson's disease, and traumatic brain injury. Its cell-permeable nature and specificity make it a valuable tool for dissecting MAPK signaling pathways in the central nervous system.
- Molecular Weight:
- 355.5
- Purity:
- ≥98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/jx-401-sih-454/
