Imatinib mesylate
Product Sizes
20 mg
£132.00
SIH-453-20MG
100 mg
£256.00
SIH-453-100MG
About this Product
- SKU:
- SIH-453
- Additional Names:
- 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamide methanesulfonate, 4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide mesylate, CGP 57148, Genfatinib, Glivec, Imatinib methanesulfonate, STI-571
- CAS Number:
- 152459-95-5
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Imatinib Mesylate is a tyrosine kinase inhibitor that selectively targets Bcr-Abl, c-Kit, and platelet-derived growth factor receptors (PDGFR). While primarily used in oncology, Imatinib has gained interest in neuroscience for its potential to modulate neuroinflammatory and neurodegenerative pathways. PDGFR signaling is involved in blood-brain barrier integrity, glial activation, and neuronal survival. Inhibition of PDGFR by Imatinib may reduce neuroinflammation and protect against neuronal damage in models of stroke, multiple sclerosis, and Alzheimer's disease. Its ability to cross the blood-brain barrier and influence kinase-driven signaling cascades makes it a valuable tool for exploring therapeutic strategies in neurodegenerative disease research.
- Molecular Weight:
- 589.7
- Purity:
- ≥98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/imatinib-mesylate-sih-453/
