CZC 54252 Hydrochloride
Product Sizes
5 mg
£198.00
SIH-439-5MG
25 mg
£613.00
SIH-439-25MG
About this Product
- SKU:
- SIH-439
- Additional Names:
- N-{2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]phenyl}methanesulfonamide hydrochloride
- CAS Number:
- 1191911-27-9, 1330003-04-7
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- CZC 54252 Hydrochloride is a potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2), a kinase genetically linked to familial and sporadic Parkinson's disease. LRRK2 mutations are associated with altered kinase activity, leading to impaired autophagy, mitochondrial dysfunction, and neuroinflammation. CZC 54252 is widely used in Parkinson's disease research to study the effects of LRRK2 inhibition on neuronal survival, protein clearance, and inflammatory responses. Its selectivity and potency make it a valuable tool for validating LRRK2 as a therapeutic target in neurodegeneration.
- Molecular Weight:
- 541.5
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/czc-54252-hydrochloride-sih-439/
