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Product Sizes
10 mg
£189.00
SIH-436-10MG
50 mg
£580.00
SIH-436-50MG
About this Product
SKU:
SIH-436
Additional Names:
Chk2 Inhibitor II, Chk2 Inhibitor II hydrate, 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide hydrate
CAS Number:
516480-79-8
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
Bml 277 is a highly selective inhibitor of checkpoint kinase 2 (Chk2), a key component of the DNA damage response pathway. In neuroscience, Chk2 is studied for its role in neuronal apoptosis and genomic stability under stress conditions. Bml 277 is used to investigate the contribution of Chk2 signaling to neurodegenerative processes, particularly in models of oxidative stress, ischemia, and neuroinflammation. Its selectivity makes it a valuable tool for dissecting DNA repair mechanisms and their impact on neuronal survival.
Molecular Weight:
363.8
Purity:
≥98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors