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Product Sizes
5 mg
£167.00
SIH-423-5MG
25 mg
£488.00
SIH-423-25MG
About this Product
SKU:
SIH-423
Additional Names:
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide, A-83-01, A83-01
CAS Number:
909910-43-6
CE/IVD:
RUO
Extra Details:
A83-01 is a selective inhibitor of TGF-B Beta type I receptor ALK5 kinase. It blocks phosphorylation of Smad2 and inhibits TGF-B Beta-induced epithelial-to-mesenchymal transition. A83-01 also inhibits the transcriptional activity induced by TGFB Beta type I receptor ALK-5, activin type IB receptor ALK-4 and nodal type I receptor ALK-7.
Molecular Weight:
421.5
Purity:
≥98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors