BzATP
Product Sizes
5 mg
SIH-420-5MG
25 mg
SIH-420-25MG
About this Product
- SKU:
- SIH-420
- Additional Names:
- 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt
- CAS Number:
- 112898-15-4
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- BzATP (2',3'-O-(4-benzoylbenzoyl)-ATP) is a potent agonist of the P2X7 receptor, exhibiting significantly greater efficacy than ATP. P2X7 receptors are ATP-gated ion channels expressed predominantly in microglia and are key mediators of neuroinflammatory responses. Activation of P2X7 by BzATP induces calcium influx, cytokine release, and inflammasome activation-processes implicated in the pathogenesis of neurodegenerative diseases such as Alzheimer's, multiple sclerosis, and amyotrophic lateral sclerosis. BzATP is also used to study purinergic signaling and glial cell activation in models of brain injury and chronic inflammation. Its high potency and receptor specificity make it a valuable tool for dissecting neuroimmune mechanisms in the CNS.
- Molecular Weight:
- 1018.97
- Purity:
- >97.7%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/agonist/bzatp-sih-420/
