MS-275
Product Sizes
10 mg
£169.00
SIH-416-10MG
50 mg
£400.00
SIH-416-50MG
About this Product
- SKU:
- SIH-416
- Additional Names:
- Entinostat; 3-pyridinylmethyl [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate, N-(2-Aminophenyl)-4-[N-(pyridine-3ylmethoxycarbonyl)aminomethyl]benzamide
- CAS Number:
- 209783-80-2
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- MS 275 (Entinostat) is a selective inhibitor of class I histone deacetylases (HDACs), which regulate chromatin structure and gene expression. In neuroscience, MS 275 is used to study epigenetic mechanisms underlying neurodevelopment, synaptic plasticity, and neurodegeneration. HDAC inhibition by MS 275 promotes histone acetylation, leading to transcriptional activation of neuroprotective genes. It has shown promise in models of Alzheimer's and Huntington's disease by enhancing cognitive function and reducing neuroinflammation. MS 275 is a valuable tool for exploring epigenetic therapies aimed at restoring neuronal health and function.
- Molecular Weight:
- 376.4
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/ms-275-sih-416/
