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Proteins and Peptides

Metformin Hydrochloride

Product Sizes
5 g
£111.00
SIH-395-5G
About this Product
SKU:
SIH-395
Additional Names:
N,N-Dimethylimidodicarbonimidic diamide hydrochloride
CAS Number:
1115-70-4
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
Metformin Hydrochloride is a widely used antidiabetic agent that improves insulin sensitivity and lowers blood glucose levels. In neuroscience, Metformin has emerged as a promising neuroprotective compound. It activates the LKB1-AMPK pathway, which inhibits mTORC1 and promotes autophagy-a key mechanism for clearing misfolded proteins and damaged organelles in neurons. Metformin has been shown to reduce alpha-synuclein phosphorylation and aggregation, making it relevant in Parkinson's disease research. It also exhibits anti-inflammatory and antioxidant effects, contributing to its potential in Alzheimer's disease and other neurodegenerative conditions. Metformin's ability to modulate energy metabolism and cellular stress responses positions it as a candidate for therapeutic repurposing in brain aging and neurodegeneration.
Molecular Weight:
165.6
Purity:
≥97%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules