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Product Sizes
5 mg
£229.00
SIH-387-5MG
25 mg
£664.00
SIH-387-25MG
About this Product
SKU:
SIH-387
Additional Names:
(6S,9aS)-Hexahydro-6-[(4-hydroxyphe-nyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(-phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-c-arboxamide
CAS Number:
847591-62-2
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
ICG-001 is a selective inhibitor of the B Beta-catenin/CBP interaction, effectively modulating Wnt/B Beta-catenin signaling pathways. In neuroscience, dysregulation of Wnt signaling has been implicated in neurodevelopmental disorders and neurodegenerative diseases. ICG-001 has been used to study neuronal differentiation, synaptic plasticity, and neuroinflammation. By targeting transcriptional coactivators, ICG-001 influences gene expression profiles associated with cell survival and neurogenesis. Its application in models of brain injury and neurodegeneration highlights its potential as a therapeutic modulator of signaling pathways critical for maintaining neuronal integrity and function.
Molecular Weight:
548.63
Purity:
>98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors