6-Formylindolo[3,2-b]carbazole (FICZ)
Product Sizes
100 ug
£175.00
SIH-383-100UG
500 ug
£541.00
SIH-383-500UG
About this Product
- SKU:
- SIH-383
- Additional Names:
- Indolo[3,2-b]carbazole-6-carbaldehyde, FICZ
- CAS Number:
- 172922-91-7
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- 6-Formylindolo(3,2-b)carbazole (FICZ) is a high-affinity endogenous ligand for the aryl hydrocarbon receptor (AhR), derived from tryptophan metabolism. FICZ rapidly induces cytochrome P450 enzymes, particularly CYP1A1, at picomolar concentrations, highlighting its potency in modulating gene expression. In neuroscience, FICZ is gaining attention for its role in regulating neuroimmune interactions and oxidative stress via AhR signaling. These pathways are increasingly implicated in neurodegenerative diseases, including multiple sclerosis and Alzheimer's disease. FICZ's ability to influence neuroinflammation and cellular detoxification positions it as a promising molecule for studying environmental and metabolic contributions to brain health.
- Molecular Weight:
- 284.3
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Biomaterials: Ligands
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/ligand/6-formylindolo32-bcarbazole-sih-383/
