Thiolutin
Product Sizes
1 mg
£186.00
SIH-375-1MG
5 mg
£574.00
SIH-375-5MG
About this Product
- SKU:
- SIH-375
- Additional Names:
- N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide
- CAS Number:
- 87-11-6
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Thiolutin is a sulfur-containing antibiotic that inhibits RNA polymerases and has been shown to block transcription initiation. In neuroscience, it is used to study transcriptional regulation and stress responses in neurons. Thiolutin also exhibits antioxidant properties and can modulate proteasome activity, making it relevant in models of oxidative stress and protein aggregation. These features are particularly important in neurodegenerative diseases where transcriptional dysregulation and oxidative damage contribute to neuronal loss.
- Molecular Weight:
- 228.3
- Purity:
- ≥98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/thiolutin-sih-375/
