Xanthohumol
Product Sizes
10 mg
£282.00
SIH-370-10MG
50 mg
£991.00
SIH-370-50MG
About this Product
- SKU:
- SIH-370
- Additional Names:
- (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(-3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)--2-propen-1-one
- CAS Number:
- 6754-58-1
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- Xanthohumol is a prenylated flavonoid and valosin-containing protein (VCP) inhibitor that has shown promise in neurodegenerative disease research. By binding to the N-domain of VCP, it disrupts autophagosome maturation, a process critical for cellular waste clearance in neurons. Impaired autophagy is a hallmark of neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Xanthohumol also exhibits potent anticancer activity by inhibiting cell proliferation and inducing apoptosis. Its dual role in modulating proteostasis and cell survival pathways makes it a valuable tool for investigating therapeutic interventions in neurodegeneration.
- Molecular Weight:
- 354.4
- Purity:
- ≥98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/xanthohumol-sih-370/
