PJ-34
Product Sizes
10 mg
£282.00
SIH-366-10MG
50 mg
£909.00
SIH-366-50MG
About this Product
- SKU:
- SIH-366
- Additional Names:
- N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,Ndimethylacetamide . HCl
- CAS Number:
- 344458-15-7
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- PJ-34 is a potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell death pathways. In neuroscience, PJ-34 is used to study neuroprotection in models of ischemia, traumatic brain injury, and neurodegeneration. PARP overactivation leads to energy depletion and neuronal death, and PJ-34 mitigates this by preserving cellular NAD⁺ levels. Its anti-inflammatory and anti-apoptotic effects make it a valuable compound for exploring therapeutic strategies aimed at reducing neuronal damage and promoting recovery in neurodegenerative conditions.
- Molecular Weight:
- 331.8
- Purity:
- ≥98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/pj-34-sih-366/
