5-Azacytidine
Product Sizes
50 mg
£107.00
SIH-345-50MG
250 mg
£188.00
SIH-345-250MG
About this Product
- SKU:
- SIH-345
- Additional Names:
- 4-Amino-1-B Beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one; Ladakamycin; U-18496; NSC-102816; 5-AzaC
- CAS Number:
- 320-67-2
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- 5-Azacytidine is a DNA methyltransferase inhibitor that incorporates into DNA and forms covalent adducts with DNMT1, leading to enzyme depletion and global DNA demethylation. This reactivates silenced genes and alters epigenetic landscapes. In neurodegenerative disease research, 5-Azacytidine is used to study the role of epigenetic regulation in neuronal differentiation, plasticity, and disease progression. It has also been shown to enhance the efficiency of stem cell reprogramming and promote differentiation into neuronal lineages, making it a valuable tool in regenerative neuroscience and epigenetic therapy development.
- Molecular Weight:
- 244.2
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/5-azacytidine-sih-345/
