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Product Sizes
50 mg
£147.00
SIH-343-50MG
About this Product
SKU:
SIH-343
Additional Names:
Benzyl [(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]carbamate; N-Benzyloxycarbonyl-Lphenylalaninylchloromethyl ketone; ZPCK
CAS Number:
26049-94-5
CE/IVD:
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Extra Details:
ZPCK (SL-01) is a small molecule that inhibits the p53-MDM2 interaction at micromolar concentrations (20 uM). It has also been shown to inhibit bovine chymotrypsin A-y, indicating potential protease inhibitory activity. By disrupting the p53-MDM2 axis, ZPCK may stabilize p53 and promote its transcriptional activity, which is relevant in both cancer biology and neurodegenerative disease models. In the nervous system, p53 plays a dual role in regulating apoptosis and neuronal survival, making ZPCK a candidate for probing p53-mediated pathways in neurodegeneration.
Molecular Weight:
331.8
Purity:
>98%
Shipping Conditions:
Ambient
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors