MDBN
Product Sizes
100 mg
£128.00
SIH-342-100MG
About this Product
- SKU:
- SIH-342
- Additional Names:
- 3,4-Methylenedioxy-B Beta-nitrostyrene; 5-[(E)-2-Nitrovinyl]-1,3-benzodioxole
- CAS Number:
- 1485-00-3
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- MDBN is an irreversible inhibitor of the AAA-ATPase p97, also known as valosin-containing protein (VCP), with an IC50 below 10 uM. p97 plays a central role in protein homeostasis, including ER-associated degradation (ERAD), autophagy, and stress granule dynamics. Mutations in p97 are linked to neurodegenerative disorders such as inclusion body myopathy and frontotemporal dementia. MDBN offers a pharmacological approach to modulate p97 activity and investigate its role in neuronal proteostasis and neurodegeneration.
- Molecular Weight:
- 193.2
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/mdbn-sih-342/
