Deguelin
Product Sizes
10 mg
£269.00
SIH-251-10MG
50 mg
£873.00
SIH-251-50MG
About this Product
- SKU:
- SIH-251
- Additional Names:
- (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
- CAS Number:
- 522-17-8
- CE/IVD:
- RUO
- Extra Details:
- Deguelin is a rotenoid compound with notable anti-cancer and neurotoxic properties. It inhibits mitochondrial complex I, leading to increased oxidative stress and apoptosis in cancer cells. However, its neurotoxicity has raised concerns, particularly due to its association with Parkinsonian symptoms in animal models. Deguelin's dual role as a therapeutic agent and neurotoxin makes it a compound of interest in neurodegenerative disease research, especially for understanding mitochondrial dysfunction and oxidative stress pathways in dopaminergic neurons.
- Molecular Weight:
- 394.42
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inducer/deguelin-sih-251/
