FK506
Product Sizes
10 mg
£172.00
SIH-214-10MG
50 mg
£335.00
SIH-214-50MG
About this Product
- SKU:
- SIH-214
- Additional Names:
- 3-(3-Pyridinyl)propyl 1-(3,3-dimethyl-2-oxopentanoyl)prolinate, Tacrolimus, Fujimycin
- CAS Number:
- 104987-11-3
- CE/IVD:
- Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- Extra Details:
- FK506, also known as Tacrolimus or Fujimycin, is a macrolide immunosuppressant with emerging neuroprotective properties. It inhibits calcineurin by forming a complex with FKBP12, thereby preventing NF-AT dephosphorylation and downstream T-cell activation. In neuroscience, FK506 has shown promise in protecting neurons from degeneration in models of antiretroviral toxic neuropathy and other neuroinflammatory conditions. Its ability to modulate calcium signaling and reduce neuroinflammation positions it as a potential therapeutic agent for neurodegenerative diseases.
- Molecular Weight:
- 804
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/fk506-sih-214/
