Difluoromethylornithine
Product Sizes
10 mg
£94.00
SIH-200-10MG
50 mg
£185.00
SIH-200-50MG
About this Product
- SKU:
- SIH-200
- Additional Names:
- N2-(Difluoromethyl)ornithine, DFMO, Eflornithine
- CAS Number:
- 70052-12-9
- CE/IVD:
- RUO
- Extra Details:
- Difluoromethylornithine (DFMO) is an irreversible inhibitor of ornithine decarboxylase, a key enzyme in polyamine biosynthesis. While primarily studied for its anti-cancer, anti-parasitic, and anti-angiogenic properties, DFMO has emerging relevance in neurodegenerative disease research. Polyamines are implicated in neuronal growth, differentiation, and synaptic plasticity, but their dysregulation contributes to neurotoxicity and oxidative stress. By modulating polyamine levels, DFMO may help mitigate excitotoxicity and inflammation in neurodegenerative conditions such as Alzheimer's disease and Huntington's disease. Its potential to reduce neuronal apoptosis and modulate neuroinflammation positions DFMO as a candidate for therapeutic intervention in neurodegeneration.
- Molecular Weight:
- 218.63
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://www.stressmarq.com/products/small-molecules/inhibitor/difluoromethylornithine-sih-200/
