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Antibodies

Anti-ROR1 Reference Antibody (zilovertamab vedotin)

Product Sizes
100 ug
£635.00
CHB266-100UG
1 mg
£2295.00
CHB266-1MG
About this Product
SKU:
CHB266
Additional Names:
IgG1|zilovertamab vedotin
Application:
Cell-based/Functional Assay, Detection/Quantitation, ELISA, FACS, Flow Cytometry
Buffer:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Zilovertamab vedotin is an ADC consisting of a ROR1-directed antibody and Monomethyl auristatin E (MMAE) used for the study of several solid tumors.
Formulation:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Immunogen:
ROR1
Isotype:
IgG1
Physical State:
Lyophilized
Purity:
>90%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
ROR1
Storage Conditions:
-70[o]C Avoid freeze/thaw cycles., 2-8[o]C
Supplier:
Sanyou Biopharmaceuticals
Type:
Antibody: Biosimilar Antibody
  • Manufacturer's Data Sheet:CHB266
Anti-ROR1 Reference Antibody (zilovertamab vedotin) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-ROR1 Reference Antibody (Zilovertamab vedotin) is 98.21%, determined by SEC-HPLC.
Immobilized human ROR1 His at 2 ug/mL can bind Anti-ROR1 Reference Antibody (Zilovertamab vedotin), The EC50 is 0.002833 ug/mL.
Anti-ROR1 Reference Antibody (Zilovertamab vedotin) inhibited the tumor growth of MDA-MB-231on NSG mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 96.6% at 10 mpk.
The endocytosis ratio Zilovertamab by Human ROR1-HEK293T cells increased with the increase of antibody concentration, and the Internalization Rate (%) reached 80% .