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Antibodies

Anti-CD79b Reference Antibody (polatuzumab vedotin-piiq)

Product Sizes
100 ug
£635.00
CHB256-100UG
1 mg
£2295.00
CHB256-1MG
About this Product
SKU:
CHB256
Additional Names:
IgG1|polatuzumab vedotin-piiq
Application:
Cell-based/Functional Assay, Detection/Quantitation, ELISA, FACS, Flow Cytometry
Buffer:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.
Formulation:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Immunogen:
CD79b
Isotype:
IgG1
Physical State:
Lyophilized
Purity:
>90%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
CD79b
Storage Conditions:
-70[o]C Avoid freeze/thaw cycles., 2-8[o]C
Supplier:
Sanyou Biopharmaceuticals
Type:
Antibody: Biosimilar Antibody
  • Manufacturer's Data Sheet:CHB256