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Antibodies

Anti-SEMA4D / CD100 Reference Antibody (pepinemab)

Product Sizes
100 ug
£385.00
CHA336-100UG
1 mg
£965.00
CHA336-1MG
About this Product
SKU:
CHA336
Additional Names:
pepinemab
Application:
Cell-based/Functional Assay, Detection/Quantitation, ELISA, FACS, Flow Cytometry
Buffer:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Anti-SEMA4D / CD100 Reference Antibody (pepinemab)(CHA336) is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
Immunogen:
SEMA4D / CD100
Isotype:
IgG4
Physical State:
Lyophilized
Purity:
>95%
Reactivities:
Human
Sequence:
QVQLVQSGAEVKKPGSSVKVSCKASGYSFSDYYMHWVRQAPGQGLEWMGQINPTTGGASYNQKFKGKATITVDKSTSTAYMELSSLRSEDTAVYYCARYYYGRHFDVWGQGTTVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGPPCPPCPAPEFLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSQEDPEVQFNWYVDGVEVHNAKTKPREEQFNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKGLPSSIEKTISKAKGQPREPQVYTLPPSQEEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSRLTVDKSRWQEGNVFSCSVMHEALHNHYTQKSLSLSLGK
Shipping Conditions:
Blue Ice
Specificity:
SEMA4D / CD100
Storage Conditions:
2-8[o]C, -70[o]C Avoid freeze/thaw cycles.
Supplier:
Sanyou Biopharmaceuticals
Type:
Antibody: Biosimilar Antibody
  • Manufacturer's Data Sheet:CHA336
Anti - Human/Mouse CD100 ( Pepinemab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti - Human/Mouse CD100 ( Pepinemab) is 100%, determined by SEC-HPLC.
Immobilized human CD100 (His Tag, 2ug/mL) can bind to Anti - Human/Mouse CD100 ( Pepinemab) with an EC50 of 0.0081 ug/mL.
Human CD100-expressing HEK293 cells were stained with Anti - Human/Mouse CD100 ( Pepinemab) , with isotype and secondary-only controls. Flow analysis showed specific binding of the antibody, with an EC50 of 0.3227 nM.
Anti - Human/Mouse CD100 ( Pepinemab) inhibited the tumor growth of CT26 on balb/c mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 76.9% at 50 mpk at D24.