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Antibodies

Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab)

Product Sizes
50 ug
CHA081-50UG
100 ug
CHA081-100UG
1 mg
CHA081-1MG
About this Product
SKU:
CHA081
Additional Names:
avelumab
Application:
Cell-based/Functional Assay, Detection/Quantitation, ELISA, FACS, Flow Cytometry
Buffer:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab)(CHA081) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hulambda. It has a predicted MW of 145.5 kDa.
Immunogen:
B7-H1 / PD-L1 / CD274
Isotype:
IgG1, kappa
Physical State:
Lyophilized
Purity:
>95%
Reactivities:
Human, Mouse, Rat, Cynomolgus, Rabbit, Dog
Sequence:
EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYIMMWVRQAPGKGLEWVSSIYPSGGITFYADTVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARIKLGTVTTVDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPG
Shipping Conditions:
Ambient
Specificity:
B7-H1 / PD-L1 / CD274
Storage Conditions:
2-8[o]C
Supplier:
Sanyou Biopharmaceuticals
Type:
Antibody: Biosimilar Antibody
  • Manufacturer's Data Sheet:CHA081
Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab) is 98.22%, determined by SEC-HPLC.
Immobilized human PD-L1 FC at 2 ug/mL can bind Anti-B7-H1 / PD-L1 / CD274 Reference Antibody (avelumab), EC50=0.03725 ug/mL.
Avelumab inhibited the tumor growth of MC38 on hLAG3 mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 32.6% at 1 mpk at D28.