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Antibodies

Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab)

Product Sizes
50 ug
CHA046-50UG
100 ug
CHA046-100UG
1 mg
CHA046-1MG
About this Product
SKU:
CHA046
Additional Names:
bemarituzumab
Application:
Cell-based/Functional Assay, Detection/Quantitation, ELISA, FACS, Flow Cytometry
Buffer:
25mM histidine, 8% sucrose, 0.01% Tween80 pH6.2
Clonality:
Recombinant Monoclonal
Concentration:
1 mg/ml
Extra Details:
Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab)(CHA046) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.24 kDa.
Immunogen:
FGFR2 / CD332
Isotype:
IgG1, kappa
Physical State:
Lyophilized
Purity:
>95%
Reactivities:
Human
Sequence:
QVQLVQSGAEVKKPGSSVKVSCKASGYIFTTYNVHWVRQAPGQGLEWIGSIYPDNGDTSYNQNFKGRATITADKSTSTAYMELSSLRSEDTAVYYCARGDFAYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Shipping Conditions:
Ambient
Specificity:
FGFR2 / CD332
Storage Conditions:
2-8[o]C
Supplier:
Sanyou Biopharmaceuticals
Type:
Antibody: Biosimilar Antibody
  • Manufacturer's Data Sheet:CHA046
Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
The purity of Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) is 100%, determined by SEC-HPLC.
SNU-16 cells were stained with Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.5368 ug/mL.
Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) -ADCC luciferase Assay on KATOIII cells. The maximum suppression factor is approximately 14.
Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) induced ADCC activity was evaluated using Human FGFR2 HEK293 Reporter Cell.The max induction fold was approximately 25.