Aquaporin 2 phospho S264 Antibody
Product Sizes
100 ul
612-401-D09-100UL
About this Product
- SKU:
- 612-401-D09
- Additional Names:
- ADH water channel, Aquaporin-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct|Aqp2
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- 0.01 M HEPES, 0.15 M Sodium Chloride
- CE/IVD:
- RUO
- Clonality:
- Polyclonal
- Extra Details:
- Aquaporin 2 antibody recognizes aquaporin 2 (AQP2) which is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans. A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells. Recently, serine-264 has been identified as a novel phosphorylation site on AQP2 and shown to be regulated by vasopressin thus implicating this site as important in AQP2 trafficking and subcellular distribution. Anti-Aquaporin 2 pS264 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
- Formulation:
- 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
- Host:
- Rabbit
- Immunogen:
- Anti-Aquaporin 2 pS264 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser264.
- Isotype:
- IgG
- Physical State:
- Liquid
- Reactivities:
- Rat
- Shipping Conditions:
- Dry Ice
- Specificity:
- Anti-Aquaporin 2 pS264 Antibody is directed against rat Aquaporin 2 protein phosphorylated at S264. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulte
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Rockland Inc
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:https://www.rockland.com/search/?searchString=612-401-D09
