sIL-15 Receptor alpha Fc
Product Sizes
20 ug
£178.82
S01-083-20UG
100 ug
£307.06
S01-083-100UG
About this Product
- SKU:
- S01-083
- Additional Names:
- soluble Interleukin-15 receptor subunit alpha, soluble IL-15RA, CD215
- translate.label.attr.clone:
- (#7H61)
- Extra Details:
- IL-15 signaling is an important factor in proliferating, activating, and immunomodulating primarily T cells. IL-15R A Alpha is an IL-15 specific, single pass membrane receptor which complexes with IL-2R B Beta and IL-2R G Gamma to form a high affinity IL-15 receptor. Additionally, the IL-15/IL-15R complex is capable of binding to IL-2 B Beta/G Gamma receptors on other cells, therefore enabling IL-15 to indirectly activate cells expressing IL-2 B Beta/G Gamma receptors. A soluble form of IL-15 receptor A Alpha is naturally produced by proteolytic cleavage of the membrane-bound precursor. This naturally occurring soluble form can act as a modulator of IL-15 signaling through the inhibition of IL-15 receptor binding. Recombinant Human sIL-15 Receptor A Alpha Fc has a calculated molecular weight of 44.4 kDa protein and contains 408 amino acid residues, which consists of the extracellular domain of IL-15R A Alpha fused to the Fc portion of human IgG. Due to glycosylation, it migrates at an apparent molecular weight of 50-60 kDa, under reducing conditions.
- Formulation:
- lyophilized
- Host:
- Rabbit
- Molecular Weight:
- 44.4 kDa
- Purity:
- ≥98%
- Reactivities:
- Human
- Sequence:
- ITCPPPMSVE HADIWVKSYS LYSRERYICN SGFKRKAGTS SLTECVLNKA TNVAHWTTPS LKCIRDPALV HQRPAPPSTV TTAGVTPQPE SLSPSGKEPA ASSPSSNNTA ATTAAIVPGS QLMPSKSPST GTTEISSHES SHGTPSQTTA KNWELTASAS HQPPGVYPQG HSDTTGGPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGK
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins