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Proteins and Peptides

Flt-3 Ligand

Product Sizes
2 ug
£178.82
R20-076-2UG
10 ug
£307.06
R20-076-10UG
About this Product
SKU:
R20-076
Additional Names:
Fms-related tyrosine kinase 3 ligand, Flt3L
Extra Details:
Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Rat Flt3-Ligand is a soluble 18.3 kDa protein consisting of 162 amino acid residues.
Formulation:
lyophilized
Host:
E. coli
Molecular Weight:
18.3 kDa
Purity:
≥ 98% by SDS-PAGE gel and HPLC analyses
Reactivities:
Rat
Sequence:
TPDCYFSHSP ISSNFHMRIS ELTDYLLKDY PVTVAINLQD EKHCKALWSL FLAHRWIEQL KTVAGSKMQK LLEDVNTEIH FVTSCTFQPL PECLRFVQTN ISHLLQDTCS QLLALKPCIG KACQNFSRCL EVQCQPDSST LLPPESPGAL GATELPKPLP RQ
Shipping Conditions:
Ambient
Storage Conditions:
Room Temperature
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins