Oncostatin M
Product Sizes
2 ug
£178.82
R20-057-2UG
10 ug
£307.06
R20-057-10UG
About this Product
- SKU:
- R20-057
- Additional Names:
- Oncostatin M
- translate.label.attr.clone:
- (#18L1)
- Extra Details:
- Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. Recombinant rat Oncostatin M is a 24-25 kDa protein, containing 215 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Mouse
- Molecular Weight:
- 24.4 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Bacteria, Human, Mouse, Non-human Primate, Other Mammal, Rat
- Sequence:
- MKRGCSSSSP KLLSQLKSQA NITGNTASLL EPYILHQNLN TLTLRAACTE HPVAFPSEDM LRQLSKPDFL STVHATLGRV WHQLGAFRQQ FPKIQDFPEL ERARQNIQGI RNNVYCMARL LHPPLEIPEP TQADSGTSRP TTTAPGIFQI KIDSCRFLWG YHRFMGSVGR VFEEWGDGSR RSRRHSPLWA WLKGDHRIRP SRSSQSAMLR SLVPR
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins