TNF-alpha
Product Sizes
5 ug
£178.82
R20-013-5UG
20 ug
£307.06
R20-013-20UG
About this Product
- SKU:
- R20-013
- Additional Names:
- Tnf; Tnfa; RATTNF; TNF-alpha
- Extra Details:
- TNF-A Alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-A Alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-A Alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant rat TNF-A Alpha is a soluble 157 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.
- Formulation:
- lyophilized
- Molecular Weight:
- 17.3 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Bacteria, Human, Mouse, Non-human Primate, Rat
- Sequence:
- MLRSSSQNSS DKPVAHVVAN HQAEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLIY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VSLLSAIKSP CPKDTPEGAE LKPWYEPMYL GGVFQLEKGD LLSAEVNLPK YLDITESGQV YFGVIAL
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins