IL-6
Product Sizes
2 ug
£178.82
R20-008-2UG
10 ug
£307.06
R20-008-10UG
About this Product
- SKU:
- R20-008
- Additional Names:
- Il6; ILg6; Ifnb2
- Extra Details:
- IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R A Alpha and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant rat IL-6 is a 21.7 kDa protein containing 187 amino acid residues.
- Formulation:
- lyophilized
- Host:
- Mouse
- Molecular Weight:
- 21.7 kDa
- Purity:
- > 98% by SDS-PAGE & HPLC analyses
- Reactivities:
- Bacteria, Human, Mouse, Rat
- Sequence:
- MFPTSQVRRG DFTEDTTHNR PVYTTSQVGG LITYVLREIL EMRKELCNGN SDCMNSDDAL SENNLKLPEI QRNDGCFQTG YNQEICLLKI CSGLLEFRFY LEFVKNNLQD NKKDKARVIQ SNTETLVHIF KQEIKDSYKI VLPTPTSNAL LMEKLESQKE WLRTKTIQLI LKALEEFLKV TMRSTRQT
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Room Temperature
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins