VEGF-A, Blocking Antibody
Product Sizes
100 ug
£976.47
mV1007m-m-100UG
About this Product
- SKU:
- mV1007m-m
- Additional Names:
- Vegfa; Vpf; Vegf; Vegf120; Vegf164; Vegf188
- Application:
- Block/Inhibit/Neutralise, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- MAB0705
- Clonality:
- Monoclonal
- Extra Details:
- Mouse VEGF (or VEGF-A) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF (isoform 164) is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 164 amino acid polypeptide chains. The antibody blocks the binding of VEGF to VEGFR-2 ( mouse FLK) and therefore the initiation of signal transduction.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant mouse VEGF
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody