VEGFR-3/FLT-4, Antagonistic
Product Sizes
100 ug
£976.47
mV1003m-m-100UG
About this Product
- SKU:
- mV1003m-m
- Additional Names:
- vascular endothelial growth factor receptor-3; Flt4; Chy; Flt-4; VEGFR3; VEGFR-3
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS
- translate.label.attr.clone:
- 9G03
- Clonality:
- Monoclonal
- Extra Details:
- VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- recombinant mouse VEGFR3 N-terminal protein
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody