VEGFR-2/KDR, Agonistic
Product Sizes
100 ug
£976.47
MV1001-3M-H-100UG
About this Product
- SKU:
- MV1001-3M-H
- Additional Names:
- vascular endothelial growth factor receptor-2 ; KDR; FLK1; CD309; VEGF receptor 2; kinase insert domain protein receptor
- Application:
- Activate/Stimulate, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- 8A01
- Clonality:
- Monoclonal
- Extra Details:
- VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. The antibody will bind near the ligand binding site of the receptor and has agonistic activity.
- Formulation:
- lyophilized
- Host:
- Mouse
- Immunogen:
- hVEGFR2 N-terminal fragment (N30-200)
- Isotype:
- IgG1
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C lyophilized. Avoid freeze/thaw cycles.
- Supplier:
- ReliaTech
- Type:
- Antibody: Monoclonal Antibody