OX40L / TNFSF4 Protein (ECD, His Tag)
Product Sizes
50 ug
£482.00
M60-190-L50-50UG
About this Product
- SKU:
- M60-190-L50
- Additional Names:
- Ath-1 Protein; Ath1 Protein; CD134L Protein; gp34 Protein; OX-40L Protein; Ox40l Protein; Tnfsf4 Protein; Tnlg2b Protein; TXGP1 Protein; Txgp1l Protein
- Buffer:
- PBS
- Extra Details:
- OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-40L is a ligand for receptor TNFRSF4/OX40. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD4-stimulated B cells, this cytokine along with CD7 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
- Formulation:
- lyophilized
- Molecular Weight:
- 18 kDa
- Purity:
- >95%
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
