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Proteins and Peptides

B Beta-NGF / Beta-NGF Protein

Product Sizes
100 ug
£494.00
M60-134-L100-100UG
About this Product
SKU:
M60-134-L100
Additional Names:
beta-NGF Protein; Ngf Protein; Ngfb Protein
Buffer:
150mM NaCl, 50mM NaAc, pH 5.5.
Extra Details:
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, A Alpha, B Beta, and G Gamma, among which, the B Beta subunit, called B Beta-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system.
Formulation:
lyophilized
Molecular Weight:
14 kDa
Purity:
>95%
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Supplier:
ReliaTech
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins