DKK-1 Protein (His Tag)
Product Sizes
1000 ug
£3341.00
M60-079-L1000-1000UG
About this Product
- SKU:
- M60-079-L1000
- Additional Names:
- DKK-1 Protein; SK Protein; UNQ492/PRO1008 Protein
- Buffer:
- PBS
- Extra Details:
- Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers.
- Formulation:
- lyophilized or frozen liquid
- Molecular Weight:
- 27.6 kDa
- Purity:
- ≥95%
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
