Carboxypeptidase B1 / CPB1 Protein (His Tag)
Product Sizes
50 ug
£494.00
M60-060-L50-50UG
About this Product
- SKU:
- M60-060-L50
- Additional Names:
- CPB Protein; PASP Protein; PCPB Protein
- Buffer:
- 25 mM MES, 100 mM NaCl; pH 6.5
- Extra Details:
- Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.
- Formulation:
- lyophilized
- Molecular Weight:
- 47 kDa
- Purity:
- ≥95%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
