CD28 / TP44 Protein (Fc Tag)
Product Sizes
1000 ug
£1682.00
M60-047-L1000-1000UG
About this Product
- SKU:
- M60-047-L1000
- Additional Names:
- Cd28 Protein
- Buffer:
- PBS
- Extra Details:
- CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
- Formulation:
- lyophilized or frozen liquid
- Molecular Weight:
- 119.2 kDa (glycosylated)
- Purity:
- ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. ≥ 95 % as determined by SEC-MALS.
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins