CD27/ TNFRSF7 Protein (ECD, mFc Tag)
Product Sizes
50 ug
£376.00
M60-044-L50-50UG
About this Product
- SKU:
- M60-044-L50
- Additional Names:
- Cd27 Protein; S152 Protein; Tnfrsf7 Protein; Tp55 Protein
- Buffer:
- PBS
- Extra Details:
- CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.
- Formulation:
- lyophilized
- Molecular Weight:
- 44.17 kDa
- Purity:
- >90%
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
