CCL12 / MCP-5 Protein (His Tag)
Product Sizes
20 ug
£329.00
M60-009-L20-20UG
About this Product
- SKU:
- M60-009-L20
- Additional Names:
- MCP-5 Protein; Mcp5 Protein; Scya12 Protein
- Buffer:
- PBS
- Extra Details:
- Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impaired fibronectin and collagen deposition and indirectly stimulated collagen degradation through upregulation of matrix metalloproteinase-2. In post-MI patients, circulating LPS levels strongly associated with the Ccl12 homologue monocyte chemotactic protein 1 (MCP-1). Both MCP-1 and MCP-5 are HIF-1 target genes and that HIF-1alpha is involved in transcriptional induction of these two chemokines in astrocytes by hypoxia.
- Formulation:
- lyophilized
- Molecular Weight:
- 10.7 kDa
- Purity:
- >90%
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Supplier:
- ReliaTech
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
